12 Day Viking River Cruise from St. Louis to Twin Cities 2025

Day 1 St. Louis, Missouri, United States

Arrive and check in to your hotel.

Day 2 St. Louis, Missouri, United States

St. Louis was once the gateway to the legendary Wild West, known for its gun-wielding cowboys and law-making sheriffs. Today, the city boasts a world-class cultural scene and one of the leading sporting attractions in the US. The St. Louis Cardinals are one of the most successful baseball clubs, having won 11 World Series championships, second only to the New York Yankees. While the Big Apple is famed for its Central Park, St. Louis has its own green space. Some of St. Louis’ most important cultural sights are located in Forest Park, including the Missouri History Museum.

Day 3 St. Louis, Missouri, United States

After breakfast, check out of your hotel.

Day 4 Hannibal, Missouri, United States

Hannibal is the childhood home of Samuel Langhorne Clemens, or Mark Twain, and the inspiration for his beloved stories of Tom Sawyer and Huckleberry Finn. Prior to the 1803 Louisiana Purchase and arrival of European settlers, a variety of indigenous Native American tribes called the area home. Hannibal grew into the primary port for steamboats and flatboats traveling the Upper Mississippi. “The Unsinkable Molly Brown,” the early 20th-century socialite, philanthropist and survivor of the Titanic tragedy, was also born here.

Day 5 Burlington, Iowa, United States

The US flag was first raised over Iowa in Burlington—in 1805—by Lieutenant Zebulon Pike during his Mississippi explorations. Later, it became an outpost for the American Fur Company, a trading enterprise founded by John Jacob Astor. In 1834, it took its present name after the Vermont birthplace of its first settler, John Gray. During the steamboat era, it was a major port along the river. Today, the city is home to many magnificent buildings on the National Register of Historic Places, including the art deco Capitol Theater and the Gothic Revival St. Paul’s Church.

Day 6 Quad Cities, Iowa, United States

Straddling the confluence of the Mississippi and Rock Rivers, the Quad Cities area comprises Davenport and Bettendorf, Iowa, and Rock Island, Moline and East Moline, Illinois. As the only section of the Mississippi that flows from east to west, it is geographically unique. Its tightly knit riverside towns thrived due to thoughtful planning and effective leadership. Today, the Quad Cities rest amid the fertile farmland known as “America’s Breadbasket”—the nation’s most expansive and scenic agricultural region—and is home to agribusiness giants including John Deere.

Day 7 Dubuque, Iowa, United States

One of Iowa’s few cities laid out among rolling bluffs, Dubuque is called the “Masterpiece on the Mississippi” for its 19th-century ingenuity and modern-day cultural evolution. Timber and boatbuilding were central to the city’s growth, with wood harvested in Minnesota and Wisconsin. The spirit of this river town lives on in the Cathedral Historic District, dotted with well-preserved buildings and authentic period lampposts. Today, the city is praised for its livability and for its riverside developments, including a museum and aquarium dedicated to the Mississippi River.

Day 8 La Crosse, Wisconsin, United States

La Crosse has a deep connection to the towering bluffs and rolling farmland of the Norskedalen, or “Norwegian Valley.” Here, a Norwegian immigrant population has created a unique culture over generations. Historic immigrant villages dot the valley still, a collection of preserved homesteads reflecting a frontier way of life. Today, La Crosse boasts numerous sites on the National Register of Historic Places. Its important architectural landmarks, along with an array of engaging statues along the riverfront, make La Crosse feel like a vast open air museum.

Day 9 Red Wing, Minnesota, United States

Red Wing is known for its Red Wing Shoes, which produced footwear for soldiers in both world wars. The city was named after a Sioux chief whose red-dyed swan wing indicated his rank. The first settlers—many from New England—arrived in the mid-1800s. German, Irish and Scandinavian immigrants followed, bringing skills in tanning, shoemaking, pottery and more. The city boasts a diversity of legacies including Red Wing Stoneware and Pottery, founded in 1877 as the nation’s first commercial potter. Today, Red Wing enjoys a place in the National Trust for Historic Preservation.

Day 10 Red Wing, Minnesota, United States

Exuding small-town charm, Red Wing shares a border with Wisconsin along the winding waterway of the Mississippi River. The city is renowned for its “impressive architecture and enviable natural environment,” according to the National Trust for Historic Preservation. Surrounded by striking landscapes, Red Wing is an attraction for nature lovers seeking unspoiled natural beauty, where numerous hiking trails and prime fishing spots abound. The city is also home to a vibrant local arts scene, with several festivals throughout the summer and fall.

Day 11 Twin Cities, Minnesota, United States

Minnesota’s two largest cities, Minneapolis and St. Paul, are located near the confluence of the Mississippi and Minnesota Rivers. Known as the “Twin Cities,” they are independent municipalities with distinct characters. Minneapolis, occupying the western side of the Mississippi, is known for its thriving arts scene and cosmopolitan vibe, with sleek skyscrapers and contemporary architecture. On the eastern bank, state capital St. Paul sits on a series of bluffs overlooking the river, exuding a quaint charm and boasting a collection of well-preserved Victorian-era buildings.

Day 12 Twin Cities, Minnesota, United States

Minneapolis and St. Paul offer a range of outdoor activities, including hiking, biking and bird watching. The Twin Cities is home to more than 500 miles of bike trails, including the scenic Gateway State Trail and the Mississippi River Trail. Hikers can explore the trails in Minnehaha Park or head to more rugged terrain at nearby Lebanon Hills or Afton State Park. Bird watchers can observe a variety of species, including bald eagles, peregrine falcons and great blue herons at the Minnesota Valley National Wildlife Refuge and the Eloise Butler Wildflower Garden.