13 Day Uniworld River Cruise from Milan to Rome 2025

Uniworld Boutique Cruises River Cruise - Milan to Rome

Grande Italia

Starting from $4,829
Ship(s): S.S. La Venezia
13 Day Uniworld River Cruise from Milan to Rome 2025 -

River Cruise Description

Begin your journey in stunning Milan, where you’ll view da Vinci’s “The Last Supper.” Stop for a tasting of rare Amarone wines on your way to romantic Venice. Embark on your cruise to treat yourself to a private evening lighting ceremony at St. Mark’s Basilica, explore the colorful facades of Burano, and sail south to discover Chioggia—a charming southern port loved by fishermen, artists, and anyone looking for unique gifts or souvenirs. Complete your spectacular Italian adventure with a stay in Rome, where a local guide will whisk you away to the city’s most charming and historic sites.




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Apr 4, 2025S.S. La VeneziaWaitlistCall Us!
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River Cruise Itinerary

Day 1 Milan

Arrive at Milan Malpensa Airport. If your cruise/tour package includes a group arrival transfer or if you have purchased a private arrival transfer, you will be greeted by a Uniworld representative and transferred to the Rosa Grand hotel.

Day 2 Milan

Day 3 Milan (Verona/Valpolicella), Transfer to Venice (Embark)

En route to Venice, you’ll stop in the literary hometown of Shakespeare’s famously star-crossed teen lovers to see the sights. Later, enjoy lunch at a historic wine estate owned by descendants of Dante and learn about one of the most unique Italian wines, Amarone di Valpolicella.

Day 4 Venice

With your early morning arrival at Doge’s Palace, you’ll be able to marvel at the estate in total peace. Wander through a Venetian neighborhood and experience daily life in an authentic Venetian residential quarter. Later in the evening, cap the day off with a private once-in-a-lifetime experience at an after-hours lighting ceremony inside St. Mark’s Basilica without the crowds.

Day 5 Venice, Mazzorbo (Burano)

Start your morning in one of two of the Veneto region’s UNESCO World Heritage cities, Vicenza or Padua. In the afternoon, you'll reboard the ship for scenic sailing across the lagoon as we head towards Mazzorbo and Burano.

Day 6 Mazzorbo, Burano, Chioggia

Day 7 Chioggia

Today, you’ll admire the greatest sites of charming and coastal Chioggia, including a stop at the local and lively market.

Day 8 Chioggia, Venice

This morning, join a sailing excursion where you’ll explore the Po Delta where the Po River and the Adriatic Sea meet. Later, during lunch, we sail back to Venice.

Day 9 Venice

As your water taxi glides past narrow side canals and the Canal Grande, you’ll arrive in style at the Rialto Bridge. The iconic stone arch bridge sits at the narrowest point of the Canal Grande and holds numerous shops and restaurants.

Day 10 Venice (Disembark), Transfer to Rome

After disembarking the ship this morning, we’ll make our way by train to the capital city of Rome. Check into the Anantara Palazzo Naiadi Rome hotel (or similar) and, if you’d like, you can join an Orientation Walk of the neighborhood around the hotel with your Local Host.

Day 11 Rome

From the Roman Empire to the Renaissance, Rome has stood at the center of Western culture many times throughout history. While eras come and go, no period of this remarkable city’s past has disappeared from its landscape. As you embark on your panoramic tour of Rome today, you’ll discover some of the greatest marks on this timeline, including the 18th-century Trevi Fountain, the 2nd-century Pantheon, and the Roman Forum, whose roots stretch back to the 8th century BCE.

Day 12 Rome

Today, you technically step out of Italy and into the smallest country in the world as you enter Vatican City, where you’ll marvel at the extravagant frescoes of the Sistine Chapel and see St. Peter’s Basilica, the largest church ever built.

Day 13 Rome

Check out of your hotel this morning. If your cruise/tour package includes a transfer, you’ll be taken to the airport to return home.
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