8 Day American Cruise Lines River Cruise from Nashville to Memphis 2025

Day 1 Nashville, TN

From the legendary Grand Ole Opry to the Country Music Hall of Fame, Nashville is the official headquarters of country music. The lively streets are lined with art galleries and unique shops that welcome you at every turn. Take time to explore historic downtown, including the famous Country Music Hall of Fame Museum and Honky Tonk Row. After a day of exploring, settle into your pre-cruise hotel and relax.

Enjoy a 1-night stay at the Gaylord Opryland Resort & Convention Center. Upon arrival, be treated to an evening performance at the Grand Ole Opry. The morning of embarkation, meet in the hotel lobby for transportation to the ship with concierge luggage service provided.

Day 2 Cruising the Cumberland River

Board your ship and enjoy a leisurely day cruising along the idyllic landscapes of the Cumberland River. As you begin your amazing journey, relax on your private stateroom balcony and admire the beautiful views that stretch out before you. Get to know fellow guests in one of the lounges or at the evening cocktail hour.

As you embark upon your journey, enjoy a Welcome Aboard Reception with cocktails, hors d’oeuvres and entertainment. Meet the crew, your onboard experts, and fellow guests. Learn more about the wonderful adventure ahead of you.

Day 3 Clarksville, TN

Discover Clarksville, named for General George Rogers Clark, a frontier fighter, Revolutionary War hero, and brother of William Clark of the Lewis and Clark Expedition. As you explore the city led by our local guides, learn how Clarksville rose as a major tobacco port during the 1800s. Tour the Don F. Pratt Memorial Museum which houses military memorabilia, or Dunbar Cave, one of the largest caves in the county.

Embark on a captivating musical journey through the heart of Tennessee as we explore Clarksville's musical history. Delve into the rich history of legendary artists that have shaped this iconic region, including Roy Acuff. Travel by motorcoach to the heart of the city where we will walk through the Tennessee Music Pathways historic sites where celebrated musicians have made their mark. Immerse yourself in the stories behind the music that echo through time, before culminating your experience at Dunbar Cave State Park, a treasure trove of musical history where big bands, including Benny Goodman, Glenn Miller, Lena Horne, and Tommy Dorsey once performed. Discover the harmonious blend of culture, nature, and music on this unforgettable adventure.

Activity Level: Moderate | ADA Accessible Yes

Built in 1898, this building originally housed a U.S. Post Office and Customs House for the flourishing tobacco trade. This architecturally fascinating structure was designed by architect, William Aicken, who was commissioned by President Grover Cleveland. It consists of Italianate ornamentation, a Far East influenced roof, Romanesque arches and Gothic copper eagles perched at the building’s four corners. The museum is among the most photographed buildings in Tennessee. It features rotating shows, fine art galleries and a sculpture garden.

Activity Level: Moderate | ADA ACCESSIBLE: Yes

Enjoy a tour and tasting at Old Glory Distilling Co., a small batch artisan distillery with a focus on crafting premium Tennessee Whiskey and Bourbon, as well as a variety of spirits including moonshine, white rum, vodka, and gin. Learn the history of the distillery as well as its operations. Be treated to a rum punch cocktail upon arrival andvisit the onsite gift shop where you can indulge in bourbon pecans as you peruse the merchandise.

Activity Level: Low| ADA ACCESSIBLE: Yes

Fort Defiance was originally a central hub for trading goods and settlement for both the American Indians and white settlers beginning in the late 18th century. During the Civil War, the Fort became a base for the Confederate Troops. But in 1862, the fort was captured by Union Troops and stayed under their command for the remainder of the war. The grounds have been well maintained and preserved since the war ended, so you will truly take a step back in time.

Activity Level: Moderate| ADA ACCESSIBLE: Yes

Downtown Clarksville is filled with entertainment and activities year-round. Take time to explore this terrific town bordered by the scenic beauty of a major river, a thriving and progressive university, and neighborhoods of people who are passionately committed to their community. Enjoy one-of-a-kind shopping, restaurants, breweries, art galleries and street art, stunning historic architecture and urban trails.

Activity Level: Low | ADA Accessible Yes

Join us for a unique experience that combines the flavors of the South with captivating entertainment and fascinating stories. Indulge in a mouthwatering southern-inspired lunch that will tantalize your taste buds. As you savor the delicious flavors, be entertained by the talented Mark Cash, nephew of the legendary Johnny Cash. Mark will share captivating stories about his iconic uncle, providing an intimate glimpse into the life and legacy of "Uncle Johnny." This experience is a perfect blend of culinary delights, live entertainment, and the rich history of one of country music's most beloved families.

Activity Level: Low | ADA Accessible: Yes

Day 4 Dover, TN

The small town of Dover is a historic treasure as well as a place of scenic beauty. Home to Fort Donelson National Park, the town played a pivot role in the Civil War as the site of a major Union victory. Within Dover is the Cross Creeks National Wildlife Refuge, an over 8,000-acre habitat of waterfowl and plant life, as well as the Land Between Lakes National Recreation Area.

Once the gateway to the Confederate Heartland, the Battle of Fort Donelson became a key victory for Ulysses Grant and Union forces. Enjoy a warm welcome at the visitor’s center by tour guides who are eager to share their knowledge. After a short introductory film, tour the grounds of the fort, surrender site, and National Cemetery while learning about the military strategies employed by each side and how the Union victory impacted the entire Civil War.

Activity Level: Low| ADA ACCESSIBLE: Partial

Travel back in time to this 1850’s working farm. Take time to walk around this historic nature preserve and interact with interpreters dressed in period clothing going about their daily chores that make the farm function. Ask questions about the animals, crops, historic artifacts, structures, and seasonal activities. Enjoy a nice stroll throughout the grounds. Or feel free to hike up your farm boots and give a helping hand to the farmers! Throughout this guided experience, you will see a carpenter shop, a house, an herb garden, a tobacco barn, animal barns, sheep, pigs, geese, chickens, people dressed in period clothing. and have the opportunity to visit the museum/visitor's center.

Activity Level: Moderate | ADA Accessible Yes

Day 5 Cruising Lake Barkley and the Cumberland River

Admire the picturesque scenery of America's Heartland, including the Kentucky Lakes and rolling landscape of 170,000 acres of protected forest. Experience a relaxing day cruising Lake Barkley and admire panoramic views of the Cumberland River from the comfort of your private balcony.

There are a variety of activities scheduled on board when the ship is underway, which vary depending on the itinerary and scheduled date. Enjoy destination-focused enrichment programs with special guest speakers who present topics related to the region and ports of call, including Art Classes, App-titude Classes (Tech Made Easy), Cooking Demonstrations, Mixology (practice of making great cocktails,) Trivia, Game Shows, and more.

Day 6 Paducah, KY

Founded by William Clark (of Lewis and Clark), Paducah is known as a National Heritage Destination with many talented culinary artists, painters, potters, and jewelers creating and displaying their works there. Also known as “Quilt City,” there is plenty to do in Paducah from shopping to visiting one the many fine museums, to participating in a hands-on creative workshop at a local art gallery.

Let our local guide take you through the quaint city of Paducah. This excursion has been carefully divided into three distinct sections to make sure you experience all that Paducah has to offer. First, explore the downtown as our local expert guide points out the areas’ many historical sites. Then, ride along the riverfront where you will witness more than 50 life-sized panoramic murals depicting elements of Paducah’s past. Endat the National Quilt Museum, the world's largest museum devoted to quilt and fiber art.

Activity Level: Low| ADA ACCESSIBLE: Yes

Explore downtown Paducah at your own pace. Visit the areas many museums and shops and stop at the riverfront to view the wall murals that tell the story of Paducah's past.

Making stops at:

Activity Level: Low| ADA Accessibility: Yes

Day 7 Cruising the Mississippi and Ohio River

Enjoy the idyllic countryside of the Ohio River and the wonder of the mighty Mississippi that inspired Mark Twain. The Ohio River was pivotal in the development and exploration of the American West and along the way we highlight much that has defined our American roots from the Civil War to bluegrass music.

There are a variety of activities scheduled on board when the ship is underway, which vary depending on the itinerary and scheduled date. Enjoy destination-focused enrichment programs with special guest speakers who present topics related to the region and ports of call, including Art Classes, App-titude Classes (Tech Made Easy), Cooking Demonstrations, Mixology (practice of making great cocktails,) Trivia, Game Shows, and more.

Day 8 Memphis, TN

Excitement resonates as you reach America’s third-largest inland port, famous for Blues, BBQ, and Elvis Presley's Graceland. The city has been at the forefront of several American cultural movements such as Civil Rights and Rock ‘n’ Roll. In fact, the city’s Beale Street is often called “America’s Most Iconic Street” due to its significance to our country’s history and contributions to the music industry.

The Memphis Rock ‘n’ Soul Museum was the first exhibition ever to have been developed by the Smithsonian Institution with another museum. The exhibition tells the story of musical pioneers who overcame racial and socio-economic barriers to create music that would influence American culture and the world. Visit the Memphis Music Hall of Fame. Explore the museum and exhibition which introduces guests to some of the greatest musicians of all time, each who contributed the city’s musical legacy. Enjoy never-before-seen memorabilia, rare video performances and interviews, interactive exhibits, and more.

Activity Level: Moderate | ADA ACCESSIBLE: Yes

Explore the captivating city of Memphis at your leisure with our convenient shuttle, making stops at:

Activity Level: Low| ADA Accessibility: Yes

Established in 1991, the National Civil Rights Museum is located at the former Lorraine Motel, where Dr. Martin Luther King Jr. was assassinated in 1968. The museum’s mission is to share the history of the American Civil Rights Movement, a tumultuous and inspiring period of change. Explore interactive exhibits and historic collections to learn how this significant era continues to shape equality and freedom today.

Activity Level: Low| ADA ACCESSIBLE: Yes

Relax and let your motorcoach guide show you the highlights of this fascinating city on the bluff. Memphis is located on the Mississippi River at the northern end of the Mississippi Delta where the Blues were born. Its history is linked to cotton and music. Along your exploration, stop at the Lorraine Motel, the location where Dr. Martin Luther King, Jr. was assassinated.

The next photo opportunity will be at the famous Sun Studio, the birthplace of rock ‘n’ roll. You will also have the option to walk through the Peabody Hotel and see the famous ducks in the fountain. Enjoy some time at the Memphis Pyramid, housing an impressive Bass Pro Shop, a Lodge, Restaurants and more. During the excursion, you will be driven through the streets of downtown Memphis. You will see Victorian Village, Orpheum Theater, Rock N Soul Museum, St. Jude's Children's Hospital, Cotton Row, Beale Street, Lauderdale Courts, early home of Elvis Presley, Sun Studio,and the Auto Zone Park. Travel by the National Civil Rights Museum and stopto see The Lorraine Motel.

Activity Level: Moderate| ADA ACCESSIBLE: Yes

For any fan of Elvis, this is the ultimate way to experience Graceland and to learn about his life and musical career. Visit Graceland Mansion and four new exhibits on the property, including the Elvis Presley Car Museum. Climb aboard one of his custom airplanes, remodeled to suit his lifestyle. Enjoy authentic Memphis cuisine at one of the themed restaurants on the property. Following Graceland, enjoy a brief city motorcoach exploration of Memphis. This excursion is perfect for any rock ‘n’ roll music lover.

This is a Signature shore excursion and should be reserved in advance. Please call (800) 894-8570 for information.

Activity Level: High| ADA Accessible: Partial

Day 9 Memphis, TN

Enjoy breakfast on board the ship, before beginning your journey home. Reflect upon your adventures and the new friends made along the way.