8 Day American Cruise Lines River Cruise from St. Louis to St. Paul 2024

Day 1 St. Louis, MO/Alton, IL

Nestled neatly beneath towering limestone bluffs, the port of Alton, Illinois, offers easy access to St. Louis and area attractions, including the National Great Rivers Museum, which tells stories of the Mississippi River’s rich history, the people that rely on the river, and its many ecosystems. Get settled into your hotel and enjoy the area at your leisure.

Each Mississippi itinerary comes complete with aHotel Stay,where you can enjoy the city at your leisure. On the morning of the cruise, meet in the hotel lobbyand we will transport you to the ship to begin your cruise. All luggage will be brought directly from the hotel and placed in your stateroom aboard the ship.

Day 2 Cruising the Mississippi River

Board your ship and be treated to a Welcome Reception. As you begin your amazing journey, relax on your private stateroom balcony and admire the beautiful views that stretch out before you. Get to know fellow guests in one of the lounges or at the evening cocktail hour.

As you embark upon your journey, enjoy a Welcome Aboard Reception with cocktails, hors d’oeuvres and entertainment. Meet the crew, your onboard experts, and fellow guests. Learn more about the wonderful adventure ahead of you.

Day 3 Hannibal, MO

Explore Hannibal, “America’s Hometown,” a mere block from the ship, where Mark Twain’s home and museum illuminate the events that shaped his life and career. Elements of his childhood adventures were woven into classics like The Adventures of Tom Sawyerand The Adventures of Huckleberry Finn.

Run your hand along Aunt Polly’s fence, explore Injun Joe’s Cave, and get reacquainted with one of the world’s most beloved authors. Explore other nearby museums and the charming downtown Main Street with unique shops, art galleries, and tasty temptations.

Explore downtown Hannibal on your own. Take time for shopping and strolling through town. Our convenient shuttle will also take you to the following:

Hannibal History Museum - Through interactive exhibits, artifacts, and historic photos, learn the story of Hannibal's remarkable past.

Mark Twain Boyhood Home &Museum - Enjoy a guided exploration of the Mark Twain Boyhood Home and Museum. This is truly a piece of Americana.

Activity Level: Low| ADA Accessibility: Yes

Step back in time and relive the adventures of Mark Twain’s days in Hannibal. Your guide will share the history of Hannibal and will show you sites of historical importance. While on your excursion, visit Rockcliffe Mansion – this American “castle” has a breathtaking view overlooking the Mississippi and is on the National Register of Historic Homes.

Activity Level: Low | ADA Accessible: No

As you arrive in Hannibal, the boyhood home of famous author Mark Twain, relive the author’s experiences that heavily influenced his writings. Visit the actual home that Mark Twain grew up in, which is surrounded by the legendary whitewashed fence of Tom Sawyer. The vivid stories told by Mark Twain come to life at this interactive museum. Visit the Becky Thatcher House, the Huck Finn Home, and the Tom and Huck Statue at the foot of Cardiff Hill. Stop at the Interpretive Center, home to 15 original Normal Rockwell paintings.

Activity Level: Low| ADA Accessibility: Yes

Join Richard Garey as Mark Twain and stroll through the streets of Hannibal, the hometown that inspired Mark Twain’s famous literary novels. Learn about its history through the author’s own words and observations and then enjoy a special performance of “Mark Twain Himself” at the Planter’s Barn Theater.

Activity Level: High| ADA Accessible: Yes

Led by a knowledgeable guide, explore the Mark Twain Cave, a labyrinth of a 260 passageways which inspired the author’s famous work, The Adventures of Tom Sawyer. Samuel Clemens (Mark Twain) played here throughout his childhood, and 170 years later, you can still see his name written on a wall in the cave.

Activity Level: Moderate| ADA Accessibility: No

Day 4 Day of Cruising

Curl up with a good book in one of our spacious lounges aboard the riverboat. Or relax on the sun deck or private balcony and enjoy the passing landscapes as we make our way along the Mississippi River from Hannibal to Muscatine.

There are a variety of activities scheduled on board when the ship is underway, which vary depending on the itinerary and scheduled date. Enjoy destination-focused enrichment programs with special guest speakers who present topics related to the region and ports of call, including Art Classes, App-titude Classes (Tech Made Easy), Cooking Demonstrations, Mixology (practice of making great cocktails,) Trivia, Game Shows, and more.

Day 5 Muscatine, IA

Located in East Central Iowa, Muscatine County's eastern edge touches the banks of the Mighty Mississippi River and is the only place where this north to south river runs east to west. Perhaps Muscatine is best known for its history as the largest button manufacturing area in the world. Learn about this idyllic town’s rich past and revel in its natural beauty, led by our engaging local guides. Explore the charming downtown, located only two blocks from our dock, where you peruse local boutiques, coffee shops, and eateries.

Enjoy 18 holes of golf at Geneva Golf & Country Club. History surrounds you at this 123 year old, championship location that is both challenging for the experienced golfer and fair and fun for the beginner. The course is a masterpiece featuring rolling terrain, rambling Geneva Creek, strategically placed bunkers, and three sets of tees that allow the course to be set up for various playing levels. In addition, you will enjoy drinks served on the course and a special take home gift consisting of balls, towel, and divot tool. Activity Level: High / ADA Accessible: No This is a Signature shore excursion and should be reserved in advance. Please call (800) 894-8570 for information.

Come visit the lovingly restored Pine Creek Grist Mill, at Wildcat Den State Park, reputed to be the oldest, most complete gristmill between the Mississippi River and the Rocky Mountains. Your friendly and experienced guide will interpret the significance of the 175 year old mill, its original milling equipment, and its picturesque setting. Listen to dramatic stories about the mill’s various owners and watch as the mill’s complex systems of belts and pulleys bring the milling process to life. With the mill being part of Iowa’s state park system, you are sure to enjoy all of nature’s glory.

Activity Level: Moderate / ADA Accessible: No

Explore the area at your leisure with our convenient motorcoach making stops at:

Activity Level: Low / ADA Accessible: Yes

Nested on 85 acres, the center offers numerous natural history exhibits featuring live reptiles, amphibians, and fish of eastern Iowa. The park also offers both paved and grass walking trails, two fishing ponds, and the Muscatine Arboretum.

Day 6 Dubuque, IA

A “Masterpiece on the Mississippi,” Dubuque is among the oldest settlements west of the Mississippi River and continues today as a primary commercial, industrial, educational, and cultural center for this region. From the ship, it’s a short walk to a cruise highlight at the incredible complex of the Smithsonian-affiliated National Mississippi River Museum & Aquarium.

View colorful Victorian mansions on a stroll through the quaint downtown area, take a ride on the world’s shortest and steepest scenic railway, or try your luck in one of Dubuque's state-of-the-art casinos. Visit one of the oldest catholic churches in the city and enjoy the lovely landscapes of the Dubuque Arboretum & Botanical Garden.

Delight in an exploration of some of the highlights of Dubuque. First, stop at Steeple Square Event Center, one of the oldest catholic churches in Dubuque which was renovated into a vibrant community gathering space. Next, arrive at Dubuque Arboretum & Botanical Garden for a guided exploration of the beautiful landscapes. Visit the Convivium Urban Farmstead, a center which celebrates the efforts of local gardeners with onsite cooking and gardening classes as well as a restaurant that serves local produce. Ride the Fenelon Place Elevator, the shortest steepest railway in the United States. Don’t forget the camera, it’s a great opportunity to get a photo of the ship at dock in the Port of Dubuque from above the bluffs.

Activity Level: Moderate | ADA ACCESSIBLE: Yes

This convenient shuttle will transport you from the ship to the center of town and back. At your leisure, explore the many districts of downtown Dubuque, including Cable Car Square, the Historic Millwork District, and Historic Old Main District, once a hideaway for notorious gangster Al Capone. Visit the Summer Farmers Market which has been located in the Upper Main district since 1845. Running daily on a continuous loop.

Activity Level: Low| ADA ACCESSIBLE: Yes

Travel to the Field of Dreams Movie Site, built by Universal Studios and known for the famous quote, “If you build it, he will come.” Released in 1989, Field of Dreams, starring Kevin Costner, was a movie that inspired millions and became an Academy Award nominee for “Best Picture of the Year.” Explore this famous site, including the baseball field, the magical corn, and the farm house in which the movie was made. After, visit the gift shop for some take-home movie memorabilia.

Activity Level: Moderate| ADA Accessibility: Yes

Take an entertaining and informative journey along the mighty Mississippi at the National Mississippi River Museum & Aquarium. The museum’s interactive exhibits will give you an inside look at the Mississippi River's past, present, and future. On this guided exploration, learn about the lives of the pioneers, explorers, and artists who once lived along the Mississippi River. Get close to nature, as you make your way through six large aquariums.

Activity Level: Medium| ADA ACCESSIBLE: Yes

Day 7 Winona, MN

Winona welcomes you with the perfect blend of modern development and old river town charm. From rolling fields of flowers to some of the most architecturally important buildings in Minnesota, enjoy a carefully crafted selection of excursions which lead you through the most intriguing sites Winona has to offer.

Explore a variety of history and art museums and admire historic homes, while listening to captivating stories told by a local guide. Board a self-exploration shuttle which takes you into the heart of downtown to learn, shop, eat, and stroll at your leisure.

Take a guided walk through Winona's historic downtown to admire great architecture, hear surprising stories, and play a fun game or two.

Activity Level: Low| ADA Accessibility: Yes

Running on a continuous loop, this guided exploration shuttle takes you from the ship to Winona's hot spots including history and art museums, historic places with beautiful architecture and stained glass, and to the heart of Downtown so you can shop, eat, and stroll at your leisure.

Activity Level: Low| ADA Accessibility: Yes

This narrated Winona boat exploration not only entertains but educates about the famed waterway, the history of Winona and its relation to the Mississippi River. Bring your camera and binoculars to view local wildlife like eagles, deer, turtles, snakes, and beaver on this mesmerizing river cruise.

Activity Level: Low

Enjoy a guided, in-depth exploration of the historic and intriguing sites around greater Winona. Stops include the Winona County History Center, Minnesota Marine Art Museum, Garvin Heights lookout with amazing views of this stretch of the Mississippi River Valley, and more.

Activity Level: Low| ADA Accessibility: Yes

Enter the quiet and rich environment of Pool 6 of the Mississippi River and observe wildlife up close within the forested backwaters. On a sit-on-top kayak or canoe, with a partner or on your own, paddle along the smooth water, stopping for a refreshment along the way. A portion of each excursion cost goes towards reclamation efforts in the surrounding Prairie Island Park area.

This is a Signature shore excursion and should be reserved in advance. Please call (800) 894-8570 for information.

Activity Level: moderate |ADA Accessibilty: No

Day 8 Red Wing, MN

Below the forested limestone bluffs of the upper Mississippi and along a narrow section of river channel, Red Wing snuggles among dozens of enchanting city parks. The town’s beauty has inspired artists, writers, and musicians for over 150 years, delivering a diverse blend of arts, entertainment, and activities for your pleasure.

Explore the historic Sheldon Performing Arts Theatre, the home of famous Red Wing shoes, and the Pottery Museum, or ride up the bluff for a remarkable view. Visit the National Eagle Center to learn more about these incredible creatures with the added thrill of admiring them up close.

Visit the National Eagle Center, offering additional up close viewing of non-releasable bald and golden eagles. Learn about the ecology, biology, and natural history of these magnificent creatures.

Activity Level: Low| ADA ACCESSIBLE: Yes

There's no better way to experience the capital city of St. Paul than on this carefully-curated excursion. Saint Paul, though the state capital, moves at a slower pace and has prided itself on architectural preservation, boasting some of the Midwest's last remaining Victorian Romanesque blocks. Led by our engaging guide, explore all this beautiful city has to offer as well as a brief stop at the Minnehaha Falls.

Note: Only available on cruises ending in St. Paul/Red Wing.

Activity Level: Low| ADA Accessibility: Yes

Travel back in time as you explore the beautiful city of Red Wing. Led by our local expert guide, view some of the most impressive Victorian homes of the period as well as the historic St. James Hotel. Visit the Pottery Museum of Red Wing and admire the numerous true vintage pieces on site such as stoneware, dinnerware, folk art, and more! Stop at the Sheldon Theatre, among the oldest operating theatres in Minnesota and host to thousands of large national touring acts, international artists, and local performers alike.

Activity Level: Low| ADA Accessibility: Yes

Explore the highlights of Red Wing on this convenient shuttle to:

Activity Level: Low / ADA Accessible: Yes

Day 9 St. Paul, MN

Enjoy easy access to the Minneapolis/St. Paul airport or extend your stay to further explore this enchanting area. The Twin Cities offer world-class art galleries, museums, and live performances. St. Paul’s Summit Avenue showcases gorgeous historic mansions built in the late 1800s. The enormous Mall of America includes more than 500 stores and an indoor waterpark and theme park. View gorgeous panoramas of the city from Mounds Park and cherish the enchantment of Minnehaha Falls with its 53-foot cascade.

Why not spend another day in St. Paul’s to explore the enchanting art galleries, world class museums, and enjoy world-class live entertainment. History buffs will enjoy a walking tour of Summit Avenue, which showcases gorgeous historic mansions built in the late 1800’s. End the day by visiting Mounds Park, where visitors are treated to a beautiful panoramic view of the city.