Find the River Cruise you’re looking for...
9 Day American Cruise Lines River Cruise from Memphis to Tulsa 2028
River Cruise Description
Step aboard for an unforgettable journey through America’s heartland on our brand-new Arkansas River cruise, where winding waterways are framed by farmland, forested bluffs, and limestone cliffs.
Experience the vibrant arts scene and iconic Art Deco architecture of Tulsa and celebrate the Native American heritage of Muskogee. Discover the frontier legacy of Fort Smith, rich with tales of lawmen and outlaws. Then, head to Little Rock, a vibrant city that features a mix of history and culture, with its riverfront parks and landmarks tied to the Civil Rights Movement.
Cruise the lower Mississippi River as you indulge in the soulful rhythms and spirit of the South. Celebrate Cleveland’s deep delta roots and the musical legacy of Memphis, home to Graceland and the iconic Beale Street.Get More Cruise Info
We'd love to connect with you and answer any questions you might have about this cruise. Fill out the form below and we'll get back with you pronto.
* Required fields.
(Note: either your Email or Phone is required—not both.)
| Departure Date | Ship | Priced From (per person) | |
|---|---|---|---|
| Apr 7, 2028 | American Serenade | $5,275 | Call Us! |
| Nov 5, 2028 | American Serenade | $5,275 | Call Us! |
River Cruise Itinerary
Day-By-Day



Day 1 Memphis, TN
Get ready to feel the vibrant soul as you cruise to Memphis. This historic gem boasts a skyline that dances along the river, lined by swaying oak trees and historic landmarks. Feel the rhythm of the city through legendary Beale Street, alive with the sounds of blues and jazz. Indulge in mouthwatering BBQ, then unwind at The Guest House, your haven in this dynamic city.Day 2 Day of Cruising
Step aboard your ship and set sail into a captivating experience. Begin with a warm welcome at the reception, an ideal place to connect with fellow travelers. As the ship elegantly cruises along the river, engage in the dynamic array of onboard entertainment. Each moment is designed to enhance your experience, promising a journey filled with delightful encounters and memorable entertainment.Day 3 Cleveland, MS
Known as the "City of Hospitality," Cleveland, Mississippi, has played a significant role in shaping the cultural landscape of the South. Its history is deeply intertwined with agriculture, particularly cotton farming, reflected in the historic downtown where remnants of the city's cotton trading past still remain.
Cleveland is also celebrated for its contributions to American music. As part of the Mississippi Blues Trail, legendary musicians such as B.B. King, Muddy Waters, and Robert Johnson have left their mark on the region. One of Cleveland's most notable cultural attractions is the GRAMMY® Museum Mississippi which pays tribute to the region's many contributions to American music.Day 4 Day of River Cruising
Today is your day to unwind and take it all in. Engage in captivating enrichment sessions and lively onboard events. Delight in gourmet cuisine and refreshing cocktails. Whether you're lounging in our spacious lounges or basking in the sun on the deck, there's endless fun to be had.Day 5 Little Rock, AR
As the state capital, Little Rock serves as a dynamic hub along the river, providing both natural beauty and urban energy. It’s a lively, welcoming destination that offers a vibrant contrast to the quieter, more serene stretches found along other parts of the Arkansas River.
Explore the riverfront, which allows you to easily access downtown attractions, historic sites, and cultural landmarks. For those seeking a deeper connection with Arkansas’s heritage, The Old State House Museum provides insight into the city’s political and social past, while the bustling River Market District showcases local cuisine, artisan shops, and live entertainment. For those who enjoy the outdoors, the nearby Arkansas River Trail and Riverfront Park offer scenic walking paths and beautiful views of the river.Day 6 Fort Smith / Van Buren, AR
Explore this historic city located at the western edge of the state, near the Oklahoma border. Originally established as a military outpost in 1817, Fort Smith played a key role in the settlement of the American West and the enforcement of federal law in Indian Territory. Today, you can enjoy its rich frontier heritage celebrated in its revitalized downtown, offering museums, cultural attractions, and a growing arts scene.
Just across the river is Van Buran. Stroll along its beautifully preserved Main Street, which features quaint shops, antique stores, and galleries housed in charming 19th-century buildings. Delight in the town’s laid-back and friendly atmosphere as you experience local culture, enjoy regional cuisine, and explore local artisan wares. Head over to Van Buren Riverfront Park, where river views and relaxed walking trails await.Day 7 Muskogee, OK
Located where the Arkansas, Verdigris, and Grand Rivers converge, Muskogee is one of Oklahoma’s most historically significant cities and a unique stop that blends Native American, Western, and musical traditions.
The city holds deep roots in Native American history, particularly as a center for the Five Civilized Tribes: Cherokee, Chickasaw, Choctaw, Creek (Muscogee), and Seminole, who were forcibly relocated to the area during the 1830s Trail of Tears. Muskogee became a symbol of resilience, where Native communities built schools, churches, and a rich cultural life, despite their hardship. The city continues to honor this legacy through museums, tribal centers, and ongoing contributions from Native communities.
Muskogee is also known for its rich musical heritage, proudly celebrated in the Oklahoma Music Hall of Fame. Here, you can learn about legendary artists like Merle Haggard, who famously sang about the town and enjoy live performances that reflect the area’s vibrant musical identity.Day 8 Tulsa, OK
As Oklahoma’s second-largest city, Tulsa is a vibrant cultural hub with deep roots in the oil boom era, a rich Native American heritage, and a thriving arts scene. It is a city that balances sophistication with a welcoming, relaxed atmosphere.
The riverfront area features beautifully maintained walking and biking trails, art installations, and green spaces, including the award-winning Gathering Place—a world-class riverfront park offering stunning gardens, nature trails, and cultural programming perfect for a leisurely afternoon.
History enthusiasts can admire the city’s Art Deco architecture, a legacy of Tulsa’s early 20th-century oil wealth. Tulsa is also home to a diverse array of museums that showcase everything from fine art and regional history to Native American culture.
Music lovers will enjoy Tulsa’s connection to legends like Woody Guthrie and the growing influence of the city's modern music scene, celebrated at the Woody Guthrie Center and Bob Dylan Center in the vibrant Arts District.Day 9 Tulsa, OK
Complete your journey in Tulsa, a city where creativity pulses through its streets and a rich cultural rhythm defines everyday life. After the tranquil Arkansas River, our journey comes to an end, but the stories, music, and moments shared will linger long after. As you disembark, the river’s timeless flow and the vibrant spirit of Tulsa leave a lasting impression and a warm farewell.Having trouble deciding which cruise is right for you?
